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Elimination and Utilization of Oxidized Guanine Nucleotides in the Synthesis of RNA and Its Precursors
Reactive oxygen species are produced as side products of oxygen utilization and can lead to the oxidation of nucleic acids and their precursor nucleotides. Among the various oxidized bases, 8-oxo-7,8-dihydroguanine seems to be the most critical during the transfer of genetic information because it c...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605631/ https://ncbi.nlm.nih.gov/pubmed/23376345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.418723 |
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