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Search for Proteins Required for Accurate Gene Expression under Oxidative Stress: ROLES OF GUANYLATE KINASE AND RNA POLYMERASE
In aerobically growing cells, in which reactive oxygen species are produced, the guanine base is oxidized to 8-oxo-7,8-dihydroguanine, which can pair with adenine as well as cytosine. This mispairing causes alterations in gene expression, and cells possess mechanisms to prevent such outcomes. In Esc...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3829146/ https://ncbi.nlm.nih.gov/pubmed/24097971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.507772 |
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