Search for Proteins Required for Accurate Gene Expression under Oxidative Stress: ROLES OF GUANYLATE KINASE AND RNA POLYMERASE

In aerobically growing cells, in which reactive oxygen species are produced, the guanine base is oxidized to 8-oxo-7,8-dihydroguanine, which can pair with adenine as well as cytosine. This mispairing causes alterations in gene expression, and cells possess mechanisms to prevent such outcomes. In Esc...

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Bibliografiske detaljer
Main Authors: Inokuchi, Hachiro, Ito, Riyoko, Sekiguchi, Takeshi, Sekiguchi, Mutsuo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
DNA and Chromosomes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829146/
https://ncbi.nlm.nih.gov/pubmed/24097971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.507772
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