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Elimination and Utilization of Oxidized Guanine Nucleotides in the Synthesis of RNA and Its Precursors

Reactive oxygen species are produced as side products of oxygen utilization and can lead to the oxidation of nucleic acids and their precursor nucleotides. Among the various oxidized bases, 8-oxo-7,8-dihydroguanine seems to be the most critical during the transfer of genetic information because it c...

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Detalhes bibliográficos
Main Authors: Sekiguchi, Takeshi, Ito, Riyoko, Hayakawa, Hiroshi, Sekiguchi, Mutsuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605631/
https://ncbi.nlm.nih.gov/pubmed/23376345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.418723
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