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Bacterial Small RNA-based Negative Regulation: Hfq and Its Accomplices

A large group of bacterial small regulatory RNAs (sRNAs) use the Hfq chaperone to mediate pairing with and regulation of mRNAs. Recent findings help to clarify how Hfq acts and highlight the role of the endonuclease RNase E and its associated proteins (the degradosome) in negative regulation by thes...

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Detalhes bibliográficos
Main Authors: De Lay, Nicholas, Schu, Daniel J., Gottesman, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605619/
https://ncbi.nlm.nih.gov/pubmed/23362267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R112.441386
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