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Chymase Mediates Angiotensin-(1-12) Metabolism in Normal Human Hearts

BACKGROUND: Identification of angiotensin-(1-12) [Ang-(1-12)] in forming Ang II by a non-renin dependent mechanism has increased knowledge on the paracrine/autocrine mechanisms regulating cardiac expression of Ang peptides. This study now describes in humans the identity of the enzyme accounting for...

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Detalhes bibliográficos
Main Authors: Ahmad, Sarfaraz, Wei, Chih-Chang, Tallaj, Jose, Dell’Italia, Louis J., Moniwa, Norihito, Varagic, Jasmina, Ferrario, Carlos M
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605226/
https://ncbi.nlm.nih.gov/pubmed/23312967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jash.2012.12.003
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