Primacy of angiotensin converting enzyme in angiotensin-(1–12) metabolism

Angiotensin-(1–12) [ANG-(1–12)], a new member of the renin-angiotensin system, is recognized as a renin independent precursor for ANG II. However, the processing of ANG-(1–12) in the circulation in vivo is not fully established. We examined the effect of angiotensin converting enzyme (ACE) and chyma...

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Главные авторы: Moniwa, Norihito, Varagic, Jasmina, Simington, Stephen W., Ahmad, Sarfaraz, Nagata, Sayaka, VonCannon, Jessica L., Ferrario, Carlos M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761328/
https://ncbi.nlm.nih.gov/pubmed/23812388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00210.2013
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