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Differential Expression of the Angiotensin-(1-12)/chymase Axis in Human Atrial Tissue
OBJECTIVE: Heart chymase rather than angiotensin converting enzyme has higher specificity for angiotensin (Ang) I conversion into Ang II in humans. A new pathway for direct cardiac Ang II generation has been revealed through the demonstration that Ang-(1-12) is cleaved by chymase to generate Ang II...
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| Publicado no: | Ther Adv Cardiovasc Dis |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5823505/ https://ncbi.nlm.nih.gov/pubmed/26082339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753944715589717 |
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