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Forebrain HCN1 channels contribute to hypnotic actions of ketamine
BACKGROUND: Ketamine is a commonly used anesthetic but the mechanistic basis for its clinically relevant actions remains to be determined. We previously showed that HCN1 channels are inhibited by ketamine and demonstrated that global HCN1 knockout mice are two-fold less sensitive to hypnotic actions...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605219/ https://ncbi.nlm.nih.gov/pubmed/23377220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318287b7c8 |
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