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HCN1 Channel Subunits Are a Molecular Substrate for Hypnotic Actions of Ketamine

Ketamine has important anesthetic, analgesic, and psychotropic actions. It is widely believed that NMDA receptor inhibition accounts for ketamine actions, but there remains a dearth of behavioral evidence to support this hypothesis. Here, we present an alternative, behaviorally relevant molecular su...

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Autori principali: Chen, Xiangdong, Shu, Shaofang, Bayliss, Douglas A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744993/
https://ncbi.nlm.nih.gov/pubmed/19158287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3481-08.2009
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