AAV9.I-1c Delivered Via Direct Coronary Infusion in a Porcine Model of Heart Failure Improves Contractility and Mitigates Adverse Remodelling

BACKGROUND: Heart failure is characterised by impaired function and disturbed Ca(2+) homeostasis. Transgenic increases in inhibitor-1 activity have been shown to improve Ca(2) cycling and preserve cardiac performance in the failing heart. The aim of this study is to evaluate the effect of activating...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Fish, Kenneth M., Ladage, Dennis, Kawase, Yoshiaki, Karakikes, Ioannis, Jeong, Dongtak, Ly, Hung, Ishikawa, Kiyotake, Hadri, Lahouaria, Tilemann, Lisa, Muller-Ehmsen, Jochen, Samulski, R. Jude, Kranias, Evangelia G., Hajjar, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605211/
https://ncbi.nlm.nih.gov/pubmed/23271792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.112.971325
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares