SERCA2a Gene Transfer Enhances eNOS Expression and Activity in Endothelial Cells

Congestive heart failure (HF) is associated with impaired endothelium-dependent nitric oxide–mediated vasodilatation. The aim of this study was to examine the effects of sarco/endoplasmic reticulum (ER) Ca(2+)-ATPase 2a (SERCA2a) gene transfer on endothelial function in a swine HF model. Two months...

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Detalhes bibliográficos
Main Authors: Hadri, Lahouaria, Bobe, Regis, Kawase, Yoshiaki, Ladage, Dennis, Ishikawa, Kiyotake, Atassi, Fabrice, Lebeche, Djamel, Kranias, Evangelia G, Leopold, Jane A, Lompré, Anne-Marie, Lipskaia, Larissa, Hajjar, Roger J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911258/
https://ncbi.nlm.nih.gov/pubmed/20461063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.77
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