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AAV9.I-1c Delivered Via Direct Coronary Infusion in a Porcine Model of Heart Failure Improves Contractility and Mitigates Adverse Remodelling
BACKGROUND: Heart failure is characterised by impaired function and disturbed Ca(2+) homeostasis. Transgenic increases in inhibitor-1 activity have been shown to improve Ca(2) cycling and preserve cardiac performance in the failing heart. The aim of this study is to evaluate the effect of activating...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605211/ https://ncbi.nlm.nih.gov/pubmed/23271792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.112.971325 |
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