Leaky ryanodine receptors in β-sarcoglycan deficient mice: a potential common defect in muscular dystrophy

BACKGROUND: Disruption of the sarcolemma-associated dystrophin-glycoprotein complex underlies multiple forms of muscular dystrophy, including Duchenne muscular dystrophy and sarcoglycanopathies. A hallmark of these disorders is muscle weakness. In a murine model of Duchenne muscular dystrophy, mdx m...

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Autors principals: Andersson, Daniel C, Meli, Albano C, Reiken, Steven, Betzenhauser, Matthew J, Umanskaya, Alisa, Shiomi, Takayuki, D’Armiento, Jeanine, Marks, Andrew R
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605002/
https://ncbi.nlm.nih.gov/pubmed/22640601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2044-5040-2-9
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