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Role of Leaky Neuronal Ryanodine Receptors in Stress-Induced Cognitive Dysfunction
The type 2 ryanodine receptor/calcium release channel (RyR2), required for excitation-contraction coupling in the heart, is abundant in the brain. Chronic stress induces catecholamine biosynthesis and release, stimulating β-adrenergic receptors and activating cAMP signaling pathways in neurons. In a...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690518/ https://ncbi.nlm.nih.gov/pubmed/22939628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.052 |
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