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PEGylation of interleukin-10 for the mitigation of enhanced pain states
The anti-inflammatory cytokine interleukin-10 (IL-10) shows promise for the treatment of neuropathic pain, but for IL-10 to be clinically useful as a short-term therapeutic its duration needs to be improved. In this study, IL-10 was covalently modified with polyethylene glycol (PEG) with the goal of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3604983/ https://ncbi.nlm.nih.gov/pubmed/19768789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.32611 |
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