FOXA1 mediates p16(INK4a) activation during cellular senescence

Mechanisms governing the transcription of p16(INK4a), one of the master regulators of cellular senescence, have been extensively studied. However, little is known about chromatin dynamics taking place at its promoter and distal enhancer. Here, we report that Forkhead box A1 protein (FOXA1) is signif...

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Main Authors: Li, Qian, Zhang, Yu, Fu, Jingxuan, Han, Limin, Xue, Lixiang, Lv, Cuicui, Wang, Pan, Li, Guodong, Tong, Tanjun
Format: Artigo
Language:Inglês
Published: European Molecular Biology Organization 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604725/
https://ncbi.nlm.nih.gov/pubmed/23443045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.35
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