FOXA1 mediates p16(INK4a) activation during cellular senescence

Mechanisms governing the transcription of p16(INK4a), one of the master regulators of cellular senescence, have been extensively studied. However, little is known about chromatin dynamics taking place at its promoter and distal enhancer. Here, we report that Forkhead box A1 protein (FOXA1) is signif...

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Autors principals: Li, Qian, Zhang, Yu, Fu, Jingxuan, Han, Limin, Xue, Lixiang, Lv, Cuicui, Wang, Pan, Li, Guodong, Tong, Tanjun
Format: Artigo
Idioma:Inglês
Publicat: European Molecular Biology Organization 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604725/
https://ncbi.nlm.nih.gov/pubmed/23443045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.35
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