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FOXA1 mediates p16(INK4a) activation during cellular senescence

Mechanisms governing the transcription of p16(INK4a), one of the master regulators of cellular senescence, have been extensively studied. However, little is known about chromatin dynamics taking place at its promoter and distal enhancer. Here, we report that Forkhead box A1 protein (FOXA1) is signif...

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Detalhes bibliográficos
Main Authors: Li, Qian, Zhang, Yu, Fu, Jingxuan, Han, Limin, Xue, Lixiang, Lv, Cuicui, Wang, Pan, Li, Guodong, Tong, Tanjun
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604725/
https://ncbi.nlm.nih.gov/pubmed/23443045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.35
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