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Thermodynamic Characterization of the Binding Interaction between the Histone Demethylase LSD1/KDM1 and CoREST

Flavin-dependent histone demethylases catalyze the posttranslational oxidative demethylation of mono- and dimethylated lysine residues, producing formaldehyde and hydrogen peroxide in addition to the corresponding demethylated protein. In vivo, the histone demethylase LSD1 (KDM1; BCH110) is a compon...

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Detalhes bibliográficos
Main Authors: Hwang, Sunhee, Schmitt, Allison A., Luteran, Andrea E., Toone, Eric J., McCafferty, Dewey G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604701/
https://ncbi.nlm.nih.gov/pubmed/21142040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101776t
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