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Properties and Molecular Determinants of the Natural Flavone Acacetin for Blocking hKv4.3 Channels

The natural flavone acacetin has been demonstrated to inhibit transient outward potassium current (I(to)) in human atrial myocytes. However, the molecular determinants of acacetin for blocking I(to) are unknown. The present study was designed to investigate the properties and molecular determinants...

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Detalhes bibliográficos
Main Authors: Wu, Hui-Jun, Sun, Hai-Ying, Wu, Wei, Zhang, Yan-Hui, Qin, Guo-Wei, Li, Gui-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603988/
https://ncbi.nlm.nih.gov/pubmed/23526953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057864
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