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Properties and Molecular Determinants of the Natural Flavone Acacetin for Blocking hKv4.3 Channels

The natural flavone acacetin has been demonstrated to inhibit transient outward potassium current (I(to)) in human atrial myocytes. However, the molecular determinants of acacetin for blocking I(to) are unknown. The present study was designed to investigate the properties and molecular determinants...

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Bibliografiske detaljer
Main Authors: Wu, Hui-Jun, Sun, Hai-Ying, Wu, Wei, Zhang, Yan-Hui, Qin, Guo-Wei, Li, Gui-Rong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603988/
https://ncbi.nlm.nih.gov/pubmed/23526953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057864
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