Transporting Antitumor Drug Tamoxifen and Its Metabolites, 4-Hydroxytamoxifen and Endoxifen by Chitosan Nanoparticles

Synthetic and natural polymers are often used as drug delivery systems in vitro and in vivo. Biodegradable chitosan of different sizes were used to encapsulate antitumor drug tamoxifen (Tam) and its metabolites 4-hydroxytamoxifen (4-Hydroxytam) and endoxifen (Endox). The interactions of tamoxifen an...

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Dades bibliogràfiques
Autors principals: Agudelo, Daniel, Sanyakamdhorn, Sriwanna, Nafisi, Shoherh, Tajmir-Riahi, Heidar-Ali
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603901/
https://ncbi.nlm.nih.gov/pubmed/23527310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060250
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