The Mannoprotein Cig1 Supports Iron Acquisition From Heme and Virulence in the Pathogenic Fungus Cryptococcus neoformans

Iron acquisition is critical for virulence of the human pathogenic fungus Cryptococcus neoformans. The cryptococcal transcript for the extracellular mannoprotein Cig1 is highly regulated by iron and abundant in iron-starved cells, suggesting a role in iron acquisition. Indeed, loss of Cig1 resulted...

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Detalhes bibliográficos
Main Authors: Cadieux, Brigitte, Lian, Tianshun, Hu, Guanggan, Wang, Joyce, Biondo, Carmelo, Teti, Giuseppe, Liu, Victor, Murphy, Michael E. P., Creagh, A. Louise, Kronstad, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603535/
https://ncbi.nlm.nih.gov/pubmed/23322859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit029
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