The Mannoprotein Cig1 Supports Iron Acquisition From Heme and Virulence in the Pathogenic Fungus Cryptococcus neoformans

Iron acquisition is critical for virulence of the human pathogenic fungus Cryptococcus neoformans. The cryptococcal transcript for the extracellular mannoprotein Cig1 is highly regulated by iron and abundant in iron-starved cells, suggesting a role in iron acquisition. Indeed, loss of Cig1 resulted...

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Detaylı Bibliyografya
Asıl Yazarlar: Cadieux, Brigitte, Lian, Tianshun, Hu, Guanggan, Wang, Joyce, Biondo, Carmelo, Teti, Giuseppe, Liu, Victor, Murphy, Michael E. P., Creagh, A. Louise, Kronstad, James W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2013
Konular:
Major Articles and Brief Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603535/
https://ncbi.nlm.nih.gov/pubmed/23322859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit029
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