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Role of Ferric Reductases in Iron Acquisition and Virulence in the Fungal Pathogen Cryptococcus neoformans

Iron acquisition is critical for the ability of the pathogenic yeast Cryptococcus neoformans to cause disease in vertebrate hosts. In particular, iron overload exacerbates cryptococcal disease in an animal model, defects in iron acquisition attenuate virulence, and iron availability influences the e...

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Hlavní autoři: Saikia, Sanjay, Oliveira, Debora, Hu, Guanggan, Kronstad, James
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911385/
https://ncbi.nlm.nih.gov/pubmed/24478097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01357-13
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