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Beta-Adrenergic Stimulation Maintains Cardiac Function in Serca2 Knockout Mice
Previous studies on Serca2 knockout (KO) mice showed that cardiac function is sustained in vivo for several weeks after knockout, whereas SERCA protein levels decrease and calcium dynamics are significantly impaired. In this study, we reconcile observed cellular and organ level contractile function...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3602781/ https://ncbi.nlm.nih.gov/pubmed/23528094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.01.042 |
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