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Increased expression of senescence markers in cystic fibrosis airways

Cystic Fibrosis (CF) is a chronic lung disease characterized by chronic neutrophilic airway inflammation and increased levels of neutrophil elastase (NE) in the airways. We have previously reported that NE treatment triggers cell cycle arrest. Cell cycle arrest can lead to senescence, a complete los...

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Detalhes bibliográficos
Main Authors: Fischer, Bernard M., Wong, Jessica K., Degan, Simone, Kummarapurugu, Apparao B., Zheng, Shuo, Haridass, Prashamsha, Voynow, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602742/
https://ncbi.nlm.nih.gov/pubmed/23316069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00091.2012
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