Increased expression of senescence markers in cystic fibrosis airways

Cystic Fibrosis (CF) is a chronic lung disease characterized by chronic neutrophilic airway inflammation and increased levels of neutrophil elastase (NE) in the airways. We have previously reported that NE treatment triggers cell cycle arrest. Cell cycle arrest can lead to senescence, a complete los...

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Bibliografiske detaljer
Main Authors: Fischer, Bernard M., Wong, Jessica K., Degan, Simone, Kummarapurugu, Apparao B., Zheng, Shuo, Haridass, Prashamsha, Voynow, Judith A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2013
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602742/
https://ncbi.nlm.nih.gov/pubmed/23316069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00091.2012
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