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Dual activation of CFTR and CLCN2 by lubiprostone in murine nasal epithelia
Multiple sodium and chloride channels on the apical surface of nasal epithelial cells contribute to periciliary fluid homeostasis, a function that is disrupted in patients with cystic fibrosis (CF). Among these channels is the chloride channel CLCN2, which has been studied as a potential alternative...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3602739/ https://ncbi.nlm.nih.gov/pubmed/23316067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00277.2012 |
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