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CFTR Is a Negative Regulator of NFκB Mediated Innate Immune Response
BACKGROUND: Dysfunctional CFTR in the airways is associated with elevated levels of NFκB mediated IL-8 signaling leading to neutrophil chemotaxis and chronic lung inflammation in cystic fibrosis. The mechanism(s) by which CFTR mediates inflammatory signaling is under debate. METHODOLOGY/PRINCIPAL FI...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2647738/ https://ncbi.nlm.nih.gov/pubmed/19247502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004664 |
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