A negative feedback loop of ICER and NF-κB regulates TLR signaling in innate immune responses

The NF-κB pathway has important roles in innate immune responses and its regulation is critical to maintain immune homeostasis. Here, we report a newly discovered feedback mechanism for the regulation of this pathway by TLR ligands in macrophages. Lipopolysaccharide (LPS) induced the expression of I...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Differ
Asıl Yazarlar: Lv, Sihan, Li, Jian, Qiu, Xinchen, Li, Weida, Zhang, Chao, Zhang, Zhen-Ning, Luan, Bing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344209/
https://ncbi.nlm.nih.gov/pubmed/28009352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.148
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