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A negative feedback loop of ICER and NF-κB regulates TLR signaling in innate immune responses
The NF-κB pathway has important roles in innate immune responses and its regulation is critical to maintain immune homeostasis. Here, we report a newly discovered feedback mechanism for the regulation of this pathway by TLR ligands in macrophages. Lipopolysaccharide (LPS) induced the expression of I...
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| Vydáno v: | Cell Death Differ |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5344209/ https://ncbi.nlm.nih.gov/pubmed/28009352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.148 |
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