Metallothionein-induced zinc partitioning exacerbates hyperoxic acute lung injury

Hypozincemia, with hepatic zinc accumulation at the expense of other organs, occurs in infection, inflammation, and aseptic lung injury. Mechanisms underlying zinc partitioning or its impact on extrahepatic organs are unclear. Here we show that the major zinc-binding protein, metallothionein (MT), i...

Full description

Saved in:

Bibliographic Details
Main Authors:	Lee, Sang-Min, McLaughlin, Joseph N., Frederick, Daniel R., Zhu, Lin, Thambiayya, Kalidasan, Wasserloos, Karla J., Kaminski, Iris, Pearce, Linda L., Peterson, Jim, Li, Jin, Latoche, Joseph D., Peck Palmer, Octavia M., Stolz, Donna Beer, Fattman, Cheryl L., Alcorn, John F., Oury, Tim D., Angus, Derek C., Pitt, Bruce R., Kaynar, A. Murat
Format:	Artigo
Language:	Inglês
Published:	American Physiological Society 2013
Subjects:	Articles
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3602737/ https://ncbi.nlm.nih.gov/pubmed/23275622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00243.2012
Tags:	Add Tag No Tags, Be the first to tag this record!

Metallothionein-induced zinc partitioning exacerbates hyperoxic acute lung injury

Similar Items