Metallothionein-induced zinc partitioning exacerbates hyperoxic acute lung injury

Hypozincemia, with hepatic zinc accumulation at the expense of other organs, occurs in infection, inflammation, and aseptic lung injury. Mechanisms underlying zinc partitioning or its impact on extrahepatic organs are unclear. Here we show that the major zinc-binding protein, metallothionein (MT), i...

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Bibliografiset tiedot
Päätekijät: Lee, Sang-Min, McLaughlin, Joseph N., Frederick, Daniel R., Zhu, Lin, Thambiayya, Kalidasan, Wasserloos, Karla J., Kaminski, Iris, Pearce, Linda L., Peterson, Jim, Li, Jin, Latoche, Joseph D., Peck Palmer, Octavia M., Stolz, Donna Beer, Fattman, Cheryl L., Alcorn, John F., Oury, Tim D., Angus, Derek C., Pitt, Bruce R., Kaynar, A. Murat
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2013
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602737/
https://ncbi.nlm.nih.gov/pubmed/23275622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00243.2012
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