Oxidative lipidomics of hyperoxic acute lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation

Reactive oxygen species have been shown to play a significant role in hyperoxia-induced acute lung injury, in part, by inducing apoptosis of pulmonary endothelium. However, the signaling roles of phospholipid oxidation products in pulmonary endothelial apoptosis have not been studied. Using an oxida...

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Autors principals: Tyurina, Yulia Y., Tyurin, Vladimir A., Kaynar, A. Murat, Kapralova, Valentyna I., Wasserloos, Karla, Li, Jin, Mosher, Mackenzie, Wright, Lindsay, Wipf, Peter, Watkins, Simon, Pitt, Bruce R., Kagan, Valerian E.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904094/
https://ncbi.nlm.nih.gov/pubmed/20418384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00035.2010
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