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NKCC2A and NFAT5 regulate renal TNF production induced by hypertonic NaCl intake

Pathways that contribute to TNF production by the kidney are not well defined. Mice given 1% NaCl in the drinking water for 3 days exhibited a 2.5-fold increase in urinary, but not plasma, TNF levels compared with mice given tap water. Since furosemide attenuated the increase in TNF levels, we hypot...

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Autores principales: Hao, Shoujin, Bellner, Lars, Ferreri, Nicholas R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602716/
https://ncbi.nlm.nih.gov/pubmed/23269645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00243.2012
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