Hepatic stellate cells and portal fibroblasts are the major cellular sources of collagens and lysyl oxidases in normal liver and early after injury

Liver fibrosis is characterized by excessive deposition of extracellular matrix proteins by myofibroblasts derived from hepatic stellate cells and portal fibroblasts. Activation of these precursors to myofibroblasts requires matrix stiffness, which results in part from increased collagen cross-linki...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Perepelyuk, Maryna, Terajima, Masahiko, Wang, Andrew Y., Georges, Penelope C., Janmey, Paul A., Yamauchi, Mitsuo, Wells, Rebecca G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2013
Schlagworte:
Liver and Biliary Tract
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602686/
https://ncbi.nlm.nih.gov/pubmed/23328207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00222.2012
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge