A matricellular protein fibulin-4 is essential for the activation of lysyl oxidase

Fibulin-4 is a matricellular protein required for extracellular matrix (ECM) assembly. Mice deficient in fibulin-4 (Fbln4(−/−)) have disrupted collagen and elastin fibers and die shortly after birth from aortic and diaphragmatic rupture. The function of fibulin-4 in ECM assembly, however, remains el...

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Vydáno v:Sci Adv
Hlavní autoři: Noda, Kazuo, Kitagawa, Kaori, Miki, Takao, Horiguchi, Masahito, Akama, Tomoya O., Taniguchi, Takako, Taniguchi, Hisaaki, Takahashi, Kazuaki, Ogra, Yasumitsu, Mecham, Robert P., Terajima, Masahiko, Yamauchi, Mitsuo, Nakamura, Tomoyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2020
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7688322/
https://ncbi.nlm.nih.gov/pubmed/33239290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc1404
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