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Disruption of claudin-18 diminishes ovariectomy-induced bone loss in mice
Claudin-18 (Cldn-18), a member of the tight junction family of proteins, is a negative regulator of RANKL-induced osteoclast differentiation and bone resorption (BR) in vivo. Since estrogen deficiency decreases bone mass in part by a RANKL-mediated increase in BR, we evaluated whether estrogen regul...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3602660/ https://ncbi.nlm.nih.gov/pubmed/23299504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00408.2012 |
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