Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F

APOBEC3F and APOBEC3G are DNA cytosine deaminases that potently restrict Human Immunodeficiency Virus-type 1 replication when the virus is deprived of its accessory protein Vif. Vif counteracts these restriction factors by recruiting APOBEC3F and APOBEC3G to an E3 ubiquitin ligase complex that media...

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Autors principals: Albin, John S., Anderson, John S., Johnson, Jeffrey R., Harjes, Elena, Matsuo, Hiroshi, Krogan, Nevan J., Harris, Reuben S.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602375/
https://ncbi.nlm.nih.gov/pubmed/23318957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.01.010
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