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AMP Activated Protein Kinase Is Indispensable for Myocardial Adaptation to Caloric Restriction in Mice

Caloric restriction (CR) is a robust dietary intervention known to enhance cardiovascular health. AMP activated protein kinase (AMPK) has been suggested to mediate the cardioprotective effects of CR. However, this hypothesis remains to be tested by using definitive loss-of-function animal models. In...

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Autors principals: Chen, Kai, Kobayashi, Satoru, Xu, Xianmin, Viollet, Benoit, Liang, Qiangrong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602170/
https://ncbi.nlm.nih.gov/pubmed/23527250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059682
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