FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer

Resistance to chemotherapy and metastases are the major causes of breast cancer-related mortality. Moreover, cancer stem cells (CSCs) play critical roles in cancer progression and treatment resistance. Previously, it was found that CSC-like cells can be generated by aberrant activation of EMT, there...

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Hauptverfasser: Hollier, Brett G., Tinnirello, Agata A., Werden, Steven J., Evans, Kurt W., Taube, Joseph H., Sarkar, Tapasree Roy, Sphyris, Nathalie, Shariati, Maryam, Kumar, Sreedevi V., Battula, Venkata L., Herschkowitz, Jason I., Guerra, Rudy, Chang, Jeffrey T., Miura, Naoyuki, Rosen, Jeffrey M., Mani, Sendurai A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602160/
https://ncbi.nlm.nih.gov/pubmed/23378344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2962
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