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Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth

Hypoxia stimulates neoangiogenesis, promoting tumor outgrowth, and triggers the epithelial-mesenchymal transition (EMT), which bestows cells with mesenchymal traits and multi-lineage differentiation potential. Here, we investigated whether EMT can confer endothelial attributes upon carcinoma cells,...

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Publicat a:Oncotarget
Autors principals: Sphyris, Nathalie, King, Cody, Hoar, Jonathan, Werden, Steven J., Vijay, Geraldine V., Miura, Naoyuki, Gaharwar, Akhilesh, Sarkar, Tapasree Roy
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8057273/
https://ncbi.nlm.nih.gov/pubmed/33889304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27940
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