Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth

Metastatic competence is contingent upon the aberrant activation of a latent embryonic program, known as the epithelial–mesenchymal transition (EMT), which bestows stem cell properties as well as migratory and invasive capabilities upon differentiated tumor cells. We recently identified the transcri...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Werden, S J, Sphyris, N, Sarkar, T R, Paranjape, A N, LaBaff, A M, Taube, J H, Hollier, B G, Ramirez-Peña, E Q, Soundararajan, R, den Hollander, P, Powell, E, Echeverria, G V, Miura, N, Chang, J T, Piwnica-Worms, H, Rosen, J M, Mani, S A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114155/
https://ncbi.nlm.nih.gov/pubmed/27292262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.203
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