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Interferons and interleukin-6 suppress the DNA-binding activity of E2F in growth-sensitive hematopoietic cells.
Transcription factor E2F binds to cellular promoters of certain growth- and cell cycle-controlling genes and forms distinct heteromeric complexes with other nuclear proteins. We show here that alpha and beta interferons (alpha, beta) and interleukin-6 abolished the E2F-containing DNA-binding complex...
Sparad:
| I publikationen: | Mol Cell Biol |
|---|---|
| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Taylor & Francis
1993
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360214/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7689148/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.9.5255 |
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