CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.

Bacterial infection stimulates the host to mount a rapid inflammatory response. A 6-base DNA motif consisting of an unmethylated CpG dinucleotide flanked by two 5' purines and two 3' pyrimidines was shown to contribute to this response by inducing polygonal B-cell activation. This stimulatory motif...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Klinman, D M, Yi, A K, Beaucage, S L, Conover, J, Krieg, A M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8610135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.7.2879
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!