CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.

Bacterial infection stimulates the host to mount a rapid inflammatory response. A 6-base DNA motif consisting of an unmethylated CpG dinucleotide flanked by two 5' purines and two 3' pyrimidines was shown to contribute to this response by inducing polygonal B-cell activation. This stimulat...

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Detaylı Bibliyografya
Asıl Yazarlar: Klinman, D M, Yi, A K, Beaucage, S L, Conover, J, Krieg, A M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1996
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC39727/
https://ncbi.nlm.nih.gov/pubmed/8610135
Etiketler: Etiketle
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