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Interleukin 4 suppresses interleukin 2 and interferon gamma production by naive T cells stimulated by accessory cell-dependent receptor engagement.

Interleukin 2 (IL-2) and interferon gamma (IFN-gamma) production by CD4+ T cells and IFN-gamma production by CD8+ T cells from naive mice in response to soluble anti-CD3 and antigen-presenting cells (APCs) were strikingly inhibited by culture in the presence of IL-4. IL-4 decreased IL-2 and IFN-gamm...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Tanaka, T, Hu-Li, J, Seder, R A, Fazekas de St Groth, B, Paul, W E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46837/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8100998/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.5914
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