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Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest.

Alpha interferon is a potent growth inhibitor of Daudi Burkitt's lymphoma cells. We show here that alpha-interferon signaling interacted simultaneously with several components of the basic cell cycle machinery, causing cells to enter into a state that had many features characteristic of the G0...

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Autori principali: Tiefenbrun, N, Melamed, D, Levy, N, Resnitzky, D, Hoffman, I, Reed, S I, Kimchi, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC231390/
https://ncbi.nlm.nih.gov/pubmed/8668211
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