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BRCA2 is epistatic to the RAD51 paralogs in response to DNA damage

Homologous recombination plays an important role in the high-fidelity repair of DNA double-strand breaks. A central player in this process, RAD51, polymerizes onto single-stranded DNA and searches for homology in a duplex donor DNA molecule, usually the sister chromatid. Homologous recombination is...

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Autori principali: Jensen, Ryan B., Ozes, Ali, Kim, Taeho, Estep, Allison, Kowalczykowski, Stephen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602134/
https://ncbi.nlm.nih.gov/pubmed/23384538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.12.007
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